Table of Commonly Used IV Solutions
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If possible do not LR or D5LR type of dextrose.
Read these to know more about the side effects of D5LR
D5LR (Lactated Ringer's Solution)
What are Lactated Ringers (Risks and Contraindications)
DLR or D5LR increases death in cardiac arrest cases
DLR and D5LR exacerabates renal problems
Please scroll down for the complete table
Please scroll down for the complete table
Table of Commonly Used IV Solutions
Use of dextrose in intravenous resuscitation fluids is common practice; however, this study indicates that 5% dextrose solutions, even if administered in physiologic quantities, greatly worsens the outcome of survivable cardiac arrest. Twelve adult male mongrel dogs were premedicated with morphine, anesthetized with halothane, instrumented, intubated, and ventilated. Each dog was first given 500 ml of either lactated Ringer's (LR) (n = 6) or 5% dextrose in LR (D5LR) (n = 6). Halothane was stopped and fibrillation was induced (60 Hz). Blood glucose just before cardiac arrest was 129 mg/dl in the LR dogs and was increased to 335 mg/dl in the D5LR dogs. After eight minutes of arrest, resuscitation, including internal cardiac massage and standard advanced cardiac life support drug protocols (modified for dogs), was begun. When stable cardiac rhythm was obtained, the chest was closed, and LR or D5LR continued until a total of 1L was given. A neurologic score (0 = normal to 100 = dead) was assigned at 1, 2, 6, and 24 hours. The LR group did not differ statistically from the D5LR group in operative time, number of defibrillatory shocks, time to spontaneous ventilation, time to extubation, or drugs required. Resuscitation was successful in all six LR and five of six D5LR group; however, by 2 hours after resuscitation and thereafter, D5LR group had a significantly greater neurologic deficit (p less than 0.05) than did the LR group. By 9 hours, four of six D5LR dogs displayed convulsive activity and died. At 24 hours the D5LR group had a greater (p less than 0.008) neurologic deficit (82 +/- 11) than did the LR group (21 +/- 7), which walked and ate. We conclude that the addition of 5% dextrose to standard intravenous fluids greatly increases the morbidity and mortality associated with cardiac resuscitation.
If possible do not LR or D5LR type of dextrose.
Read these to know more about the side effects of D5LR
D5LR (Lactated Ringer's Solution)
What are Lactated Ringers (Risks and Contraindications)
DLR or D5LR increases death in cardiac arrest cases
DLR and D5LR exacerabates renal problems
Please scroll down for the complete table
Please scroll down for the complete table
Table of Commonly Used IV Solutions
Name of
Solution
|
Type of
Solution
|
Ingredients
in
1-Liter
|
Uses
|
Complications
|
0.45% Sodium
Chloride
Shorthand Notation:
½NS
|
Hypotonic
pH 5.6
|
77 mEq Sodium
77 mEq Chloride
|
hypotonic hydration; replace sodium and chloride; hyperosmolar diabetes
|
if too much is mixed with
blood cells during
transfusions, the cells will pull water into them and rupture
|
0.9% Sodium
Chloride
Shorthand Notation: NS
|
Isotonic
pH 5.7
|
154 mEq Sodium
154 mEq Chloride
|
isotonic hydration; replace sodium and chloride; alkalosis; blood transfusions
(will not hemolyze blood cells)
|
None known
|
3% Sodium Chloride
|
Hypertonic
pH 5.0
|
513 mEq Sodium
513 mEq Chloride
|
symptomatic hyponatremia due to excessive sweating,
vomiting, renal impairment, and excessive water intake
|
rapid or continuous infusion can
result in hypernatremia or hyperchloremia
|
5% Sodium Chloride
|
Hypertonic
pH 5.8
|
855 mEq Sodium
855 mEq Chloride
|
||
5% Dextrose in
Water
Shorthand Notation: D5W
|
Isotonic
pH 5.0
|
5 grams dextrose
(170 calories/liter)
|
isotonic hydration; provides some
calories
|
water intoxication
and dilution of body's
electrolytes with long, continuous infusions
|
10% Dextrose in
Water
Shorthand Notation: D10W
|
Hypertonic
pH 4.3
|
10 grams dextrose
(340 calories/liter)
|
may
be infused peripherally;
hypertonic hydration;
provides some calories
|
|
5% Dextrose in 1/4
Strength (or 0.25%) Saline
Shorthand Notation:
D5¼NS
|
Hypertonic
pH 4.4
|
5 grams Dextrose
34 mEq Sodium
34 mEq Chloride
|
fluid replacement;
replacement of sodium, chloride and some calories
|
vein irritation
because of
acidic pH, causes agglomeration (clustering) if used with blood
transfusions;
hyperglycemia with rapid
infusion leading to osmotic
|
5% Dextrose in 0.45
Sodium Chloride
Shorthand Notation:
D5½NS
|
Hypertonic
pH 4.4
|
5 grams Dextrose
77 mEq Sodium
77 mEq Chloride
|
hypertonic fluid replacement;
replace sodium, chloride, and some calories
|
diuresis
|
5% Dextrose in
Normal Saline
Shorthand Notation: D5NS
|
Hypertonic
pH 4.4
|
5 grams Dextrose
154 mEq Sodium
154 mEq Chloride
|
hypertonic fluid replacement; replace sodium,
chloride and some calories
|
|
Ringer’s Injection,
U.S.P.
|
Isotonic
pH 5.8
|
147 mEq Sodium
4 mEq Potassium
4 mEq Calcium
155 mEq Chloride
|
electrolyte
replacement;
hydration; often used to replace extracellular fluid losses
|
rapid
administration leads
to excessive
introduction of electrolytes
and leads to fluid
overload and congestive
conditions; provides
no
calories and is not an adequate maintenance solution if abnormal fluid losses are present
|
Lactated Ringer’s
Shorthand Notation: LR
|
Isotonic
pH 6.6
|
130 mEq Sodium
4 mEq Potassium
3 mEq Calcium
109 mEq Chloride
28 mEq Sodium
Lactate (provides 9
calories/liter)
|
isotonic hydration; replace electrolytes and
extra- cellular fluid losses; mild to
moderate acidosis (the lactate
is metabolized
into
bicarbonate which counteracts the
acidosis)
|
not enough electrolytes
for maintenance; patients with hepatic disease
have trouble metabolizing the lactate;
do not use if lactic
acidosis is present
|
5% Dextrose in Lactated Ringer’s Injection
Shorthand Notation: D5LR
|
Hypertonic
pH 4.9
|
5 grams Dextrose
(170 calories/liter)
130 mEq Sodium
4 mEq Potassium
3 mEq Calcium
109 mEq Chloride
28 mEq Sodium
Lactate (provides 9
calories/liter)
|
hypertonic hydration;
provides some calories;
replace electrolytes and extra- cellular fluid losses; mild
to moderate acidosis (the lactate is metabolized into
bicarbonate which counteracts the
acidosis), the dextrose
minimizes glycogen
depletion
|
Surgery. 1986 Sep;100(3):505-11.
Dextrose containing intravenous fluid impairs outcome and increases death after eight minutes of cardiac arrest and resuscitation in dogs.
Abstract
- PMID:
- 3738770
- [PubMed - indexed for MEDLINE]
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